Old Version of PHRM 8010 website

Lectures

• These are links that are specifically on the Wiki site. If a link is not present check ELC new.

Date	Title	Link
	Lecture 1
January 11, 2022	Lead discovery and binding fundamentals
	Presentation rubrics discussion with examples
	Capstone Project Example: Basics of the Immune System
	Lecture 2
January 13, 2022	Drug targets and epigenetics
	Installation and introduction to Python programming	Link
	Students select assignments and literature discussion
	Lecture 3

General

• Pharm 8010 Assignments
• Python Programming
  • Chemoinformatics
    • Pybel Module Tutorial
    • Rdkit Module Tutorial
    • Introduction to Cheminformatics
    • Chemoinformatic Exercises in Python
  • Bionformatics
    • Biopython Tutorial
    • Tutorials of Bioinformatics in Python
    • Tutorials with Biopython
  • Pygame
    • https://www.techwithtim.net/tutorials/game-development-with-python/pygame-tutorial/pygame-animation/
    • https://medium.com/iothincvit/pygame-for-beginners-234da7d3c56f
• R Programming
  • Chemoinformatics
    • Chemoinformatics tutorial in R
• Mass Spectrometry
  • Pro pi- Mass Spec Simulator
  • Mass Spectroscopy Fragment Finder Calculator
• Chemoinformatics and Bioinformatics
  • Online resources for Bioinformatics
  • Article about Chemoinformatics
• Molecular docking
  • Small Molecule docking
• Molecular descriptors
  • https://pypi.org/project/mordred/
• Online
  • Prot Pi - Calculate the isoelectric point of your biologic
  • ProtParam tool Biologic Tool
    • Molecular weight
    • Theoretical pI
    • Amino acid composition
    • Atomic composition
    • Extinction coefficient
    • Estimated half-life
    • Instability index
    • Aliphatic index
    • Grand average of hydropathicity (GRAVY)
  • Rosetta Docking
    • https://www.rosettacommons.org/demos/latest/tutorials/Protein-Protein-Docking/Protein-Protein-Docking