Difference between revisions of "PHRM 8010"

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= International Students =
= Computer Programming =
*[[Python Programming]]
 
= Dr. Roberts' Assignments =
 
* These are assignments that Dr. Roberts is responsible for. This does not apply to other lecturers in the course.
'''Assignment #1:''' [https://hygieia.rx.uga.edu/pharmwiki/index.php/Graphing_and_Data_Analysis Graphing and Data Analysis]


* I have had native speakers in Chinese (several) and Italian attest to the accuracy of [https://www.deepl.com/translator DeepL Translate] to translate English into their native languages.
* You can do the project that is explained or something more detailed.
* I have had a native speaker attest to the accuracy of [https://translate.yandex.com/ Yandex] to translate English into Arabic.
*For speaking text in various languages, AWS Polly seems to be the best.  


= Lecture 1- Introduction to Drug Lead Discovery =
'''Assignment #2:''' [[NMR Spectrometer Simulator]] (10 out of 50 points)
*[[Installing Software for PHRM 8010]]


= Lecture 2- Drug Targets and Epigenetics =
* Dr. Zheng's part on organic chemistry = 25 points
* Dr. Bartlett's part on M.S. spectrometry = 15 points
* Dr. Robert's part with the NMR spectrometer simulator = 10 points


* [[Basic Programming with Python]]
'''Assignment #3''': [https://hygieia.rx.uga.edu/pharmwiki/index.php/Bioinformatics_and_Chemoinformatics Bioinformatics and Chemoinformatics]


= Lecture 3- Detection Methods =
* Requires installation of the Jupyter Lab IDE in Anaconda with Python version 3.7.1.1
*Recommend setting up a separate environment for doing this assignment
*If you have a small molecule drug for your Capstone project, pick three different methods to analyze your small molecule drug.
*If you have a biologic drug for your Capstone project, pick three different methods to analyze your small drug.
'''Assignment #4: Biologics-related presentation and discussion'''


* [[Basic Programming with Python]]
* Dr. Kennedy's assignment.
* [https://www.w3schools.com/python/matplotlib_intro.asp Basic Plotting with Python]


= Lecture 4- Enzyme Kinetics =
'''Assignment #5: Essay on a newly developed biologic'''


* [https://gilgi.org/blog/biochemical-kinetics-reaction-velocities/ Fitting Michaelis-Menten Kinetics with Python]
* Dr. Kennedy's assignment.:  


= Computer Programming =
'''Assignment #6:''' [[Molecular and Homology Modeling project]]
 
* You can do this project on your drug and your biological target.
*Since we never talked about homology modelling, it has been cancelled as part of the assignment.
 
= NMR Challenge =


* [[Beginner's Guide and Instructions to Programming in Python]]
# [[Tutorials for the NMR challenge]].
# [https://hygieia.rx.uga.edu/labwiki/index.php/Pharm_8010_Processing_and_Analyzing_Protein_and_Small_Molecule_Data#Small_Molecule Small molecule NMR analysis of progesterone].<ref name=":0">You will need the password for the labwiki.org website to access this.</ref>
# [https://hygieia.rx.uga.edu/labwiki/index.php/Pharm_8010_Processing_and_Analyzing_Protein_and_Small_Molecule_Data#Protein Small molecule NMR analysis of ubiquitin.]<ref name=":0" />


= Fun Stuff =
= Capstone Presentation- Drugs and Targets =
* [https://hygieia.rx.uga.edu/pharmwiki/index.php/Table_of_Drugs_and_Targets Table of Drugs and Targets]
**You will have to pick a drug and a target. Each person will have a unique one. Please email it to me.


# [[Wordle Helping Program]]
* [[Possible Outline for the Capstone Presentation]]
** When possible, you can use your drug (small molecule or biologic) and your biological target for the assignments.


= Future Course =
= Potentially Useful Information =


* [[PHRM 8010 Course Outline]]
*I have had native speakers in Chinese (several) and Italian attest to the accuracy of [https://www.deepl.com/translator DeepL Translate] to translate English into their native languages.
* I have had a native speaker attest to the accuracy of [https://translate.yandex.com/ Yandex] to translate English into Arabic.
*For speaking text in various languages, [https://aws.amazon.com/polly/ AWS Polly] seems to be the best.
*[[Chemical Class versus a Drug Class]]


= Old =
= Old =


* [[Old Version of PHRM 8010 website]]
* [[Old Version of PHRM 8010 website]]
= References and Notes =
<references />

Latest revision as of 15:58, 20 April 2022

Computer Programming

Dr. Roberts' Assignments

  • These are assignments that Dr. Roberts is responsible for. This does not apply to other lecturers in the course.

Assignment #1: Graphing and Data Analysis

  • You can do the project that is explained or something more detailed.

Assignment #2: NMR Spectrometer Simulator (10 out of 50 points)

  • Dr. Zheng's part on organic chemistry = 25 points
  • Dr. Bartlett's part on M.S. spectrometry = 15 points
  • Dr. Robert's part with the NMR spectrometer simulator = 10 points

Assignment #3: Bioinformatics and Chemoinformatics

  • Requires installation of the Jupyter Lab IDE in Anaconda with Python version 3.7.1.1
  • Recommend setting up a separate environment for doing this assignment
  • If you have a small molecule drug for your Capstone project, pick three different methods to analyze your small molecule drug.
  • If you have a biologic drug for your Capstone project, pick three different methods to analyze your small drug.

Assignment #4: Biologics-related presentation and discussion

  • Dr. Kennedy's assignment.

Assignment #5: Essay on a newly developed biologic

  • Dr. Kennedy's assignment.:

Assignment #6: Molecular and Homology Modeling project

  • You can do this project on your drug and your biological target.
  • Since we never talked about homology modelling, it has been cancelled as part of the assignment.

NMR Challenge

  1. Tutorials for the NMR challenge.
  2. Small molecule NMR analysis of progesterone.[1]
  3. Small molecule NMR analysis of ubiquitin.[1]

Capstone Presentation- Drugs and Targets

Potentially Useful Information

  • I have had native speakers in Chinese (several) and Italian attest to the accuracy of DeepL Translate to translate English into their native languages.
  • I have had a native speaker attest to the accuracy of Yandex to translate English into Arabic.
  • For speaking text in various languages, AWS Polly seems to be the best.
  • Chemical Class versus a Drug Class

Old

References and Notes

  1. 1.0 1.1 You will need the password for the labwiki.org website to access this.